Allografts can either be from a living or cadaveric source.
Organs that have been successfully transplanted include the heart, kidneys, brain, liver, lungs, pancreas, intestine, and thymus.
Some of the key areas for medical management are the problems of transplant rejection, during which the body has an immune response to the transplanted organ, possibly leading to transplant failure and the need to immediately remove the organ from the recipient.When possible, transplant rejection can be reduced through serotyping to determine the most appropriate donor-recipient match and through the use of immunosuppressant drugs.Organs and/or tissues that are transplanted within the same person's body are called autografts.Transplants that are recently performed between two subjects of the same species are called allografts.Sometimes an autograft is done to remove the tissue and then treat it or the person before returning it (examples include stem cell autograft and storing blood in advance of surgery).
In a rotationplasty, a distal joint is used to replace a more proximal one; typically a foot or ankle joint is used to replace a knee joint.
The person's foot is severed and reversed, the knee removed, and the tibia joined with the femur.
An allograft is a transplant of an organ or tissue between two genetically non-identical members of the same species.
The dual operations actually required three surgical teams including one to remove the heart and lungs from a recently deceased initial donor.
The two living recipients did well and in fact had an opportunity to meet six weeks after their simultaneous operations.
Most human tissue and organ transplants are allografts.